LENTIGINOSIS GENITAL PDF

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We studied the clinical and histopathologic characteristics of melanotic macules of the penis and vulva. The 10 lesions studied were relatively large up to 2 cm , multifocal, irregular in outline, and had variegated pigmentation.

Most were regarded as clinically atypical in appearance. Histologic examination of the lesions showed basal layer hyperpigmentation, slight melanocytic hyperplasia, epithelial hyperplasia, and stromal melanophages.

No cytologic atypia of melanocytes was detectable. Information is insufficient at present to predict the natural history of genital lentiginosis or its relation to mucocutaneous melanoma.

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Full-text links Cite Favorites. Abstract We studied the clinical and histopathologic characteristics of melanotic macules of the penis and vulva. Similar articles [Atypical pigmented penile macules]. Laguna C, et al. Actas Dermosifiliogr. PMID: Spanish. Genital lentigines and melanocytic nevi with superimposed lichen sclerosus: a diagnostic challenge. El Shabrawi-Caelen L, et al. J Am Acad Dermatol. PMID: Dermoscopic features of mucosal melanosis.

Mannone F, et al. Dermatol Surg. Pigmented lesions of the vulva. Rock B. Dermatol Clin. PMID: Review. Chancroid: clinical variants and other findings from an epidemic in Dallas County, McCarley ME, et al. Show more similar articles See all similar articles. Pilarski R. Cancers Basel. Hengge UR, Meurer M. Hengge UR, et al. Publication types Research Support, Non-U. Gov't Actions. MeSH terms Adult Actions. Aged Actions. Biopsy Actions. Female Actions. Humans Actions. Hyperplasia Actions.

Male Actions. Middle Aged Actions. Full-text links [x] Elsevier Science. Copy Download.

BADSHAH NAMDAR BY HUMAYUN AHMED PDF

Irregular, Pigmented Genital Macules

We studied the clinical and histopathologic characteristics of melanotic macules of the penis and vulva. The 10 lesions studied were relatively large up to 2 cm , multifocal, irregular in outline, and had variegated pigmentation. Most were regarded as clinically atypical in appearance. Histologic examination of the lesions showed basal layer hyperpigmentation, slight melanocytic hyperplasia, epithelial hyperplasia, and stromal melanophages. No cytologic atypia of melanocytes was detectable. Information is insufficient at present to predict the natural history of genital lentiginosis or its relation to mucocutaneous melanoma.

ALEX MIHAI STOENESCU PDF

Genital Lentiginosis: A Clinical and Histopathologic Study

Constantine Stratakis said at a meeting of the Society for Pediatric Dermatology. Understanding the common etiologic pathway in lentiginosis syndromes may help in developing therapeutic strategies and identifying individuals with less frequent or nonclassic presentations of such syndromes, said Dr. Stratakis, head of the section on endocrinology and genetics and chief of the heritable disorders branch at the National Institute of Child Health and Human Development, in Bethesda, Md. Some inherited and sporadic lentiginoses such as a labial melanotic macule J. Another condition not linked with tumors is benign lentiginosis, an autosomal dominant condition that is more frequently found in blacks and people of mixed race. Its molecular etiology is unknown. But other lentiginoses have more phenotypic variability and are associated with a predisposition to tumors:.

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